Double-edged blinde, hemorrhagic or cardioembolic cognitive impairment
نویسندگان
چکیده
I have read the article entitled “Cognitive function and adherence to anticoagulation treatment in patients with atrial fibrillation” by Jankowska-Polańska, et al., with great interest. The investigators reported that cognitive impairment is an independent determinant of compliance with pharmacological therapy in elderly patients with atrial fibrillation (AF). Lower adherence, beyond the assessment of cognitive function, is related to the age of patients. AF is associated with late-life dementia. This association is not only seen in vascular dementia, but also in Alzheimer’s disease (AD). It has been reported that AF may be associated with higher risk of cognitive function impairment. One important possible explanation is the increased incidence of stroke. Ott, et al., have demonstrated that even among AF patients without stroke, AF is still associated with dementia and AD. Both vascular dementia and AD had been reported to be associated with AF. CHADS2 score (congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke) has been reported to be of used for risk stratification regarding stroke recurrence in patients with AF, and also to predict AF recurrence after ablation and predict AF complications among AF patients. Chou, et al., reported that CHADS2 score is a useful predictor for the development of vascular dementia as well as AD in patients with AF. In this context, AF is associated with an increased risk of impaired cognitive function. In this study, adherence to anticoagulation therapy and relationship between cognitive functions are evaluated and correlation of results with CHADS2 score may be beneficial.
منابع مشابه
Effects of Boswellia serrata on Improvement of Memory Impairment in Patients with Mild Cognitive Impairment: A Double-blind, Randomized, Placebo-controlled Study
Background: Mild cognitive impairment (MCI) is the stage between the expected cognitive decline of normal aging and the more serious decline of dementia. In the present study, the effect of Boswellia serrata (BS) on improvement of memory impairment in patients with MCI was investigated. Methods: In this single-center randomized double-blind placebo-controlled ...
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